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Brand Names
Gablofen, Kemstro, Lioresal

Baclofen Information

Baclofen is a muscle relaxer and an antispastic agent.Baclofen can be used to deal with muscle symptoms including spasm, pain, and stiffness.Baclofen is sometimes used to treat muscle spasms and other symptoms in individuals with disease or injury of the spinal cord.Baclofen may also be used for purposes not listed in this medication guide.

Used for treatment: Reversible Spasticity, Severe cerebral origin Spasticity, Severe spinal cord origin Spasticity

Baclofen is a direct agonist in GABAB receptors. The exact mechanism of action of Baclofen isn’t fully known. It is capable of inhibiting both monosynaptic and polysynaptic reflexes at the spinal level, possibly by hyperpolarization of afferent terminals, although actions at supraspinal sites may also occur and contribute to its clinical impact.

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How to use baclofen

Follow all instructions on your prescription label. Your physician may change your dose to be certain to have the best results. Do not use this medication in bigger or smaller quantities or for longer than recommended. Call your health care provider if your muscle symptoms don’t improve, or if they get worse. Don’t quit using baclofen or you may have withdrawal symptoms like hallucinations or even a seizure.

Ask your doctor how to stop using this medicine.

Side Effects

  • low blood pressure (hypotension)
  • weakness
  • nausea
  • insomnia
  • frequent urination
  • dizziness
  • confusion
  • constipation
  • drowsiness
  • headache
  • fatigue


Usage can lead to decrease in brain function. In addition to the chance of brain function that is gloomy, the use of baclofen and tricyclic antidepressants may cause muscle weakness. Usage of baclofen and monoamine oxidase inhibitors can lead to low blood pressure in addition to depression of brain function. Since baclofen can raise blood sugar, when baclofen is begun doses of medications might have to be corrected.

Baclofen Withdrawal and Baclofen Detox