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Pletal
Cilostazol Information
Cilostazol is a vasodilator which is employed by relaxing the muscles on your blood vessels to help them dilate. Dilates arteries that supply blood to your legs. Blood also improves by keeping platelets in the blood from clotting and sticking together.Cilostazol is used to treat the symptoms of intermittent claudication. This illness causes blood circulation to the legs, leading to pain when walking.
Cilostazol improves your capacity to walk longer distances.Cilostazol might also be used for purposes.
Cilostazol and many of its metabolites are cyclic AMP (cAMP) phosphodiesterase III inhibitors (PDE III inhibitors), inhibiting phosphodiesterase activity and suppressing cAMP degradation with a resultant increase in cAMP in platelets and blood vessels, resulting in inhibition of platelet aggregation and vasodilation.
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How to use cilostazol
Follow all instructions. Don’t take this medicine in smaller or bigger amounts or for longer than suggested. Cilostazol is usually taken on an empty stomach, at least 30 minutes before or 2 hours after supper or breakfast. Take the medication. Continue using the medicine and tell your physician if your symptoms do not improve after 4 months of treatment. Store at room temperature away from moisture and heat.
Side Effects
- rapid or irregular heartbeat
- diarrhea
- unusual bleeding or bruising
- headache
- muscle pain
- nausea
- swelling of the arms, hands, feet, ankles, or lower legs
- stomach pain
- heartburn
Interactions
By blocking the action of enzymes that destroy cilostazol the concentration of cilostazol increases. Though not specifically studied, a similar interaction may happen with ketoconazole, itraconazole, fluconazole, miconazole, fluvoxamine, fluoxetine , nefazodone and sertraline. Diltiazem and omeprazole increase concentrations of cilostazol.
The possibility of effects could raise. A dose of 50 mg should be considered as drugs that might raise the concentration of cilostazol also are being used. Combining pletal along with different drugs that interfere with the blood clotting process might increase the chances of bleeding. The absorption of cilostazol increases. The concentration of cilostazol could increase. Consequently, grapefruit juice should not be taken by individuals on cilostazol.