Cyclophosphamide Monohydrate

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Brand Names
Cytoxan, Neosar

Cyclophosphamide monohydrate Information

Cyclophosphamide is an cancer medication that interferes with the rise and spread of cancer cells in the human body.Cyclophosphamide can be used to treat various types of cancer. Cyclophosphamide is also Utilized to treat cases of nephrotic syndrome In children. Cyclophosphamide may also be used for purposes.

Used for treatment: Acute Lymphoblastic Leukaemias, Advanced Alibert-Bazin syndrome, Histiocytic lymphoma, Metastatic gestational trophoblastic tumor, Mixed-cell type lymphoma, Recurrent Pericarditis, Refractory Small cell lung cancer, Refractory immune thrombocytopenia, Relapsed Wilm's tumor

Alkylating agents work by three distinct mechanisms: 1) attachment of alkyl groups to DNA bases, resulting in the DNA being fragmented by repair enzymes in their own attempts to substitute the alkylated bases, preventing DNA synthesis and RNA transcription from the affected DNA, 2) DNA damage via the formation of cross-links (bonds between atoms in the DNA) which prevents DNA from becoming split for regeneration or transcription, and 3) the induction of mispairing of the nucleotides resulting in mutations.

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How to use cyclophosphamide monohydrate

Adhere to all instructions on your prescription label. Don’t take this medication at smaller or larger quantities or for longer than advocated.

Side Effects

  • vomiting
  • weight loss
  • loss of appetite
  • nausea
  • temporary or permanent sterility
  • diarrhea
  • stomach pain
  • temporary hair loss
  • changes in skin or nail color
  • mouth sores
  • menstrual changes


Allopurinol enhances cyclophosphamide’s ability to reduce generation of blood cells. Cyclophosphamide raises the action of blood thinners such as warfarin raises the incidence of heart failure that is due to doxorubicin, and decreases the effectiveness of antibiotics ciprofloxacin. Quick GuidePancreatic Cancer Symptoms, Causes, and Treatment