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Dimenhydrinate is a antihistamine that reduces the effects of chemical histamine in the body.Dimenhydrinate is used to treat or protect against nausea, vomiting, and dizziness associated with motion sickness.Dimenhydrinate may also be used for purposes not listed in this medication guide.
The mechanism where some antihistamines exert their antiemetic, anti–motion sickness, and antivertigo consequences isn’t exactly known but may be related to their fundamental anticholinergic actions. They diminish vestibular stimulation and depress labyrinthine function. An action on the medullary chemoreceptive trigger zone may also be involved from the antiemetic effect. Dimenhydrinate is a competitive antagonist at the histamine H1 receptor, and this is broadly distributed in the human brain. Dimenhydrinate’s anti-emetic impact is most likely because of H1 antagonism from the circulatory system within the brain.
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How to use dimenhydrinate
Use as prescribed by your doctor, or exactly as directed on the label. Do not use in larger or smaller quantities or for longer than recommended. For best results, take dimenhydrinate 30 to 60 minutes prior to any activity that may trigger motion sickness or before traveling. You may take dimenhydrinate with or without food. Inform the physician beforehand in case you have chosen dimenhydrinate if you need surgery.
Store at room temperature away from heat and moisture.