Doxepin Hydrochloride

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Brand Names
Adapin, Prudoxin, Silenor, SINEquan, Zonalon

Doxepin hydrochloride Information

This Medicine guide Offers information Concerning the Utilization of doxepin To treat anxiety or depression. Silenor is. Doxepin is a tricyclic antidepressant. Doxepin affects chemicals.Doxepin Is utilized in the treatment of symptoms of melancholy and/or anxiety associated with psychiatric illnesses, alcoholism, or manic-depressive conditions.

Doxepin might also be utilized for purposes.

Used for treatment: Anxiety, Depression, Depression, Involutional, Insomnia, Lichen simplex chronicus, Neurotic depression, Pain, Neuropathic, Moderate, refractory Atopic dermatitis

The mechanism of action of doxepin is not totally understood. It’s thought that like amitriptyline, doxepin enriches the actions of norepinephrine and dopamine by blocking their reuptake in the adrenal gland. But, doxepin weakly inhibits the reuptake of dopamine. Doxepin may also act on histamine H1-receptors, leading to sedative effects, and ОІ-adrenergic receptors. It is also an antagonist of 5-hydroxytryptamine (serotonin) receptors, alpha-1 adrenergic receptor, and muscarinic cholinergic receptors.

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How to use doxepin hydrochloride

Follow all directions. Your physician may change your dose to be certain you get the best outcomes. Don’t take this medicine in bigger or smaller quantities or for longer than suggested. Measure doxepin oral concentrate with the exceptional dropper. Don’t use a regular table spoon. Ask your pharmacist for one, if you do not have a dose-measuring dropper. Empty the measured dose in the medicine dropper to a small glass of pineapple juice, milk, orange juice, pineapple juice, lemon juice, prune juice, or water.

Don’t use a drink that is carbonated or coconut oil to mix doxepin oral focus. Stir and drink most of it away. Do not store it. Do not quit using doxepin suddenly, or you could have unpleasant withdrawal symptoms. Ask your physician when you quit using doxepin, to prevent withdrawal symptoms. It might take around 3 months before your symptoms improve.

Keep using the medication and tell your doctor if your symptoms don’t improve. Store at room temperature away from heat, moisture, and light.

Side Effects

  • Common side effects of doxepin include sleepiness, nausea and upset stomach.
  • Common side effects of doxepin cream include burning or stinging at site of application, dry mouth, and drowsiness.


Tricyclic antidepressants , such as doxepin, shouldn’t be taken with any of the monoamine oxidase inhibitor class of antidepressants or other medications that inhibit monoamine oxidase like linezolid [Zyvox] and methylene blue. Such combinations may lead to coma, high blood pressure, tremor, hyperactivity, confusion, and death. Doxepin should not be administered for at least 14 days after stopping. Drug that influence heart rhythm such as amiodarone, bepridil , and disopyramide should not be combined with doxepin as it also impacts heart rhythm.

Doxepin’s breakdown increases and can increase doxepin blood flow, possibly causing unwanted effects.

How to pronounce doxepin (Sinequan) (Memorizing Pharmacology Flashcard)