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Adapin, Prudoxin, Silenor, SINEquan, Zonalon
Doxepin Information
This Medicine guide provides information To deal with depression or anxiety. Silenor is. Doxepin is a tricyclic antidepressant. Doxepin affects chemicals in the brain that may become unbalanced.Doxepin Is utilized as a treatment for symptoms of depression and/or stress connected with psychiatric conditions alcoholism, or manic-depressive ailments.
Doxepin might also be utilized for purposes not listed in this medication guide.
The mechanism of action of doxepin isn’t totally understood. It’s thought that such as amitriptyline, doxepin enhances the actions of norepinephrine and dopamine by blocking their reuptake in the neuronal membrane. But, doxepin weakly inhibits the reuptake of dopamine. Doxepin can also act on histamine H1-receptors, leading to sedative effects, and ОІ-adrenergic receptors. It is also an antagonist of 5-hydroxytryptamine (serotonin) receptors, alpha-1 adrenergic receptor, and muscarinic cholinergic receptors.
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How to use doxepin
Follow all directions. Your physician may change your dose to be certain that you get the best outcomes. Do not take this medication in bigger or smaller amounts or for longer than advised. Measure doxepin oral focus with the distinctive dropper supplied. Do not use a regular table spoon. If you do not have a dose-measuring dropper, ask your pharmacist for one. Drain the dose in the medicine dropper into a little glass of water, milk, orange juice, grapefruit juice, lemon juice, prune juice, or pineapple juice.
Don’t use even a carbonated drink or grape juice to mix oral concentrate. Stir the mixture and drink all of it away. Don’t store it for later usage. Do not quit using doxepin abruptly, or you might have withdrawal symptoms. Ask your physician when you quit using doxepin how to avoid withdrawal symptoms. It may take up to 3 months before your symptoms improve. Keep using the medication and inform your physician if your symptoms don’t improve.
Store at room temperature away from heat, moisture, and lighting.
Side Effects
- Common side effects of doxepin include sleepiness, nausea and upset stomach.
- Common side effects of doxepin cream include burning or stinging at site of application, dry mouth, and drowsiness.
Interactions
Tricyclic antidepressants , such as doxepin, shouldn’t be taken with any of the monoamine oxidase inhibitor class of antidepressants or other drugs that inhibit monoamine oxidase like linezolid [Zyvox] and intravenous methylene blue. Such combinations may lead to confusion, high blood pressure, tremor, hyperactivity, coma, and death. Doxepin should not be administered for at least 14 days after stopping. Drug that influence heart rhythm such as amiodarone, bepridil , and disopyramide should not be mixed with doxepin as it also affects heart rhythm.
Cimetidine increases the breakdown of doxepin and can raise doxepin blood flow inducing side effects from doxepin.