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Esomeprazole magnesium dihydrate Information
Esomeprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach.Esomeprazole is used to treat symptoms of gastroesophageal reflux disorder And conditions. Esomeprazole is also utilised to promote healing of erosive esophagitis . Esomeprazole may also be offered to stop ulcer caused by infection with helicobacter pylori , or from the use of nonsteroidal anti-inflammatory medications .Esomeprazole isn’t for immediate relief of heartburn symptoms.Esomeprazole may also be used for purposes.
Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H /K -ATPase in the gastric parietal cell. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.
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How to use esomeprazole magnesium dihydrate
Use exactly as directed on the label, or as prescribed by your physician. Don’t use in larger or smaller quantities or for longer than suggested. This medication is given for 4 to 8 weeks. If you need healing time your doctor may suggest a course of treatment. Take each dose with a complete glass of water.
Esomeprazole ought to be taken at least one hour prior to a meal. To make swallowing easier, you may open the esomeprazole capsule and sprinkle the medicine. Swallow away without chewing. Do not store the mixture for later usage. Esomeprazole could be given through a nasogastric feeding tube. Open the capsule and sprinkle the medication. Mix of water in 50 milliliters. Put the plunger and shake the mixture well. Make sure that there aren’t any medicine granules.
Attach to the NG tube and push the plunger down to empty the syringe. Then flush the tube with more water to scrub the contents down. Take this medicine for the total period of time. Your symptoms may improve before the condition is fully treated. You can develop an vitamin B-12 deficiency, if you utilize esomeprazole for longer than 3 decades. Talk to your physician if you create it, about how to manage this illness.
Call your physician if your symptoms don’t improve or if they get worse when you are taking this medicine. Esomeprazole may cause results and you might have to stop using the medication for a short period in front of a test. Tell any doctor who treats you that you’re using this medication. Store at room temperature away from heat and moisture.
Side Effects
- abdominal pain
- nausea
- gas
- dry mouth
- headache
- constipation
- drowsiness
- diarrhea
Interactions
By lowering the elimination of diazepam from the 19, the concentration in blood flow of diazepam potentially cans raise. Esomeprazole may have fewer drug interactions compared to omeprazole. The absorption of certain drugs may be affected by stomach acidity. Consequently PPIs that decrease stomach acid also reduce the absorption and concentration and increase the absorption and concentration. This may result in decreased effectiveness of increased or ketoconazole digoxin toxicity, respectively.
Through unknown mechanisms, esomeprazole may increase blood levels of saquinavir and decrease blood levels of nelfinavir and atazanavir , Hence, nelfinavir or atazanavir shouldn’t be administered with esomeprazole, and doctors should think about reducing the dose of saquinavir in order to prevent side effects from saquinavir. Clopidogrel is converted into its active form by enzymes in the liver. Esomeprazole possibly can decrease the activity of clopidogrel and lowers the activity of these enzymes.
Esomeprazole should not be used with clopidogrel. Esomeprazole increases the concentration of cilostazol and its metabolites. Cilostazol’s dose should be reduced by 100 mg twice daily to 50 mg twice daily when given with esomeprazole. Blood levels of tacrolimus and methotrexate may boost.