Esomeprazole Magnesium

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Brand Names

Esomeprazole magnesium Information

Esomeprazole is a proton pump inhibitor that reduces the amount of acid produced in the stomach.Esomeprazole is used to treat symptoms of gastroesophageal reflux disorder And other conditions. Esomeprazole is also utilized to promote healing of erosive esophagitis . Esomeprazole may also be offered to stop gastric ulcer brought on by infection with helicobacter pylori , or by the use of nonsteroidal anti-inflammatory drugs .Esomeprazole is not for instant relief of asthma symptoms.Esomeprazole may also be used for purposes not listed in this medication guide.

Used for treatment: Erosive Esophagitis(EE), GERD, Gastric ulcer caused by NSAID, Heartburn, Helicobacter Pylori Infections, Stress Ulcers, Zollinger-Ellison Syndrome, Maintenance of healing Erosive esophagitis, Postendoscopy Bleeding

Esomeprazole is a proton pump inhibitor that inhibits gastric acid secretion by specific inhibition of the H /K -ATPase in the gastric parietal cell. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.

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How to use esomeprazole magnesium

Use exactly as directed on the label, or as prescribed by your physician. Don’t use in bigger or smaller quantities or for longer than recommended. This medicine is given for 4 weeks to 6 weeks. Should you need recovery time, your physician may recommend another course of treatment. Take each dose with a complete glass of plain water. Esomeprazole should be taken at least one hour prior to a meal.

Swallow it whole. To make swallowing easier, you might open the esomeprazole capsule and sprinkle the medicine into a spoonful of applesauce or pudding. Swallow away without chewing. Don’t save the mixture for later usage. Esomeprazole could be given via a nasogastric feeding tube. Open the capsule and sprinkle the medication. Mix at 50 milliliters of water. Place the plunger and shake the mixture. Make certain there aren’t any medication granules. Attach to the NG tube and push the plunger down into empty the syringe into the tube.

Flush the tube with more water to wash off the contents down. Take this medicine for the entire period of time. If you utilize esomeprazole for more you could develop an vitamin B-12 deficiency. Speak to your physician if you create it about ways to handle this condition. Call your physician if your symptoms do not improve or if they become worse as you are taking this medicine.

Esomeprazole can cause results with specific medical evaluations, and you may want to stop using the medicine for a short time. Store at room temperature away from moisture and heat.

Side Effects

  • abdominal pain
  • nausea
  • gas
  • dry mouth
  • headache
  • constipation
  • drowsiness
  • diarrhea


The concentration in blood of diazepam potentially cans raise by lowering the removal of diazepam. Esomeprazole might have fewer drug interactions than omeprazole. The absorption of certain drugs may be affected by stomach acidity. Therefore PPIs that decrease stomach acid also reduce the absorption and concentration and increase the absorption and concentration.

This can result in decreased efficacy of ketoconazole or raised digoxin toxicity, respectively. Through unknown mechanisms, esomeprazole may boost blood levels of saquinavir and reduce blood levels of nelfinavir and atazanavir , Therefore, nelfinavir or atazanavir should not be administered with esomeprazole, and physicians should think about reducing the dose of saquinavir in order to prevent unwanted effects from saquinavir. Clopidogrel is converted into its active form by enzymes from the liver.

Esomeprazole potentially can decrease the activity of clopidogrel and lowers the activity of those enzymes. Esomeprazole shouldn’t be used with clopidogrel. Esomeprazole increases the concentration of cilostazol and its metabolites. Cilostazol’s dose ought to be reduced by 100 mg twice per day to 50 mg twice when given with esomeprazole. Esomeprazole may increase blood levels of tacrolimus and methotrexate.

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