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Esomeprazole Information
Esomeprazole is.Esomeprazole is used to treat symptoms of gastroesophageal reflux disorder And conditions. Esomeprazole is also utilised to encourage healing of erosive esophagitis . Esomeprazole may also be given to prevent ulcer brought on by infection with helicobacter pylori , or from the use of drugs .Esomeprazole isn’t for prompt relief of asthma symptoms.Esomeprazole may also be used for purposes not listed in this medication guide.
Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H /K -ATPase in the gastric parietal cell. By acting specifically on the proton pump, Esomeprazole blocks the final step in acid production, thus reducing gastric acidity.
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How to use esomeprazole
Use as prescribed by your physician, or exactly as directed on the label. Don’t use in smaller or larger quantities or for longer than recommended. This medication is generally given for 4 weeks to 6 weeks. Your doctor may suggest another course of treatment if you need healing time. Take each dose with a complete glass of plain water. Esomeprazole should be taken a minumum of one hour before a meal. Do not crush, chew, break, or open a capsule. Swallow it whole. You may open the esomeprazole capsule and sprinkle the medicine to make swallowing easier.
Swallow away without chewing. Do not save the mixture for later use. Esomeprazole can be given through a feeding tube. Open the capsule and sprinkle the medication. Mix of water at 50 milliliters. Set the plunger into the syringe and shake the mixture well. Make certain that there are no medication granules stuck at the tip of the syringe. Attach into the NG tube and push the plunger down into empty the syringe into the tube. Then flush the tube with more water to scrub off the contents down.
Take this medication for the whole amount of time. Your symptoms may improve before the condition is completely treated. If you use esomeprazole for more you could develop an vitamin B-12 deficiency. Speak with your physician if you develop it, about ways to handle this condition. Call your doctor if your symptoms don’t improve or if they get worse while you are taking this medication. Esomeprazole may cause results with medical tests, and you might need to quit using the medication for a short time prior to a test.
Tell any doctor who treats you that you are currently using this medicine.
Side Effects
- abdominal pain
- nausea
- gas
- dry mouth
- headache
- constipation
- drowsiness
- diarrhea
Interactions
By decreasing the removal of diazepam the concentration in blood flow of diazepam possibly cans raise. Esomeprazole may have fewer drug interactions compared to omeprazole. The absorption of certain drugs may be affected by stomach acidity. Therefore PPIs that reduce stomach acid also reduce the absorption and concentration and increase the absorption and concentration in blood of digoxin.
This may result in reduced effectiveness of increased or ketoconazole digoxin toxicity. Through unknown mechanisms, esomeprazole may increase blood levels of saquinavir and decrease blood levels of nelfinavir and atazanavir , Hence, nelfinavir or atazanavir shouldn’t be administered with esomeprazole, and physicians should think about reducing the dose of saquinavir to be able to prevent unwanted effects from saquinavir.
Clopidogrel is converted to its active form by enzymes from the liver. Esomeprazole potentially can decrease the action of clopidogrel and lowers the action of those enzymes. Esomeprazole should not be used with clopidogrel. Esomeprazole raises the concentration of cilostazol and its metabolites. Cilostazol’s dose should be decreased from 100 mg twice daily to 50 mg daily when given with esomeprazole.
Blood levels of methotrexate and tacrolimus may increase.