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Luvox, Luvox CR
Fluvoxamine maleate Information
Fluvoxamine is a selective serotonin reuptake inhibitor antidepressant. Fluvoxamine affects chemicals in the brain which could be unbalanced in people with symptoms. Fluvoxamine is used as a treatment for social anxiety disorder , or obsessive-compulsive ailments involving actions or recurring ideas.Fluvoxamine might be utilized for purposes not listed in this medication guide.
The precise mechanism of action of fluvoxamine hasn’t been fully ascertained, but appears to be linked to its inhibition of CNS neuronal uptake of serotonin. Fluvoxamine blocks the reuptake of dopamine in the serotonin reuptake pump of the neuronal membrane, enhancing the activity of serotonin on 5HT1A autoreceptors. In-vitro studies suggest that fluvoxamine is significantly more potent than clomipramine, fluoxetine, and desipramine as a serotonin-reuptake inhibitor. Studies also have revealed that fluvoxamine has almost no affinity for 1- or two-adrenergic, -adrenergic, muscarinic, dopamine Dtwo, histamine H1, GABA-benzodiazepine, opiate, 5-HT1, or 5-HT2 receptors.
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How to use fluvoxamine maleate
Fluvoxamine is taken at night. Follow all directions. Your dose may change. Do not take this medication in larger or smaller quantities or for longer than recommended. You could take fluvoxamine with or without food. Don’t crush, chew, break, or start an capsule. You should not quit using fluvoxamine. Follow the directions of your doctor about tapering your dose.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not being used.
Side Effects
- agitation
- drowsiness
- nervousness
- headache
- insomnia
- lack of energy
- dizziness
- nausea
- vomiting
Interactions
All SSRIs, including fluvoxamine, shouldn’t be taken with any of the monoamine oxidase inhibitor class of antidepressants such as medications that inhibit monoamine oxidase such as intravenous methylene blue and linezolid. Such combinations may lead to confusion, higher blood pressure, tremor, and increased activity.
Fluvoxamine should not be administered within 14 days of discontinuing an MAO inhibitor, and MAO inhibitors should not be administered within 14 days of stopping fluvoxamine. Similar reactions occur if fluvoxamine is blended with other medications, by way of instance, tryptophan, St. John’s wort, meperidine, and tramadol that increase serotonin in the brain. Fluvoxamine can inhibit the removal of clozapine. Fluvoxamine can also inhibit the removal and increase the blood levels of theophylline, alprazolam, and triazolam resulting in side effects from these drugs.
Fluvoxamine may increase the effect of warfarin, resulting in excessive bleeding. Warfarin therapy should be monitored more frequently. Combining SSRIs other medications that affect bleeding or nonsteroidal anti-inflammatory drugs might increase the probability of upper gastrointestinal bleeding. Fluvoxamine may increase blood levels of tizanidine, thioridazine, alosetron, and pimozide, leading to increased side effects of the drugs.