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Galantamine Information
Galantamine enhances the use of nerve cells in the brain. It works by preventing the breakdown of a chemical . People with dementia have lower amounts of this chemical, which is very important to the processes of memory, thinking, and reasoning.Galantamine is used in the treatment of mild to moderate Alzheimer’s type dementia.Galantamine might also be used for purposes not listed in this medication guide.
Galantamine is a phenanthrene alkaloid along with a reversible, competitive acetylcholinesterase inhibitor. It is not structurally related to other acetylcholinesterase inhibitors. Galantamine’s proposed mechanism of action involves the reversible inhibition of acetylcholinesterase, which prevents the hydrolysis of acetycholine, resulting in an increased concentration of acetylcholine at cholinergic synapses. Galantamine also binds allosterically with nicotinic acetylcholine receptors and may possibly potentiate the activity of agonists (such as acetylcholine) in these receptors.
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How to use galantamine
Follow all instructions. Your doctor may change your dose. Do not use this medicine in smaller or bigger amounts or for longer than advised. Even the galantamine extended-release capsule is usually taken once per day in the morning. Follow your physician’s instructions. The short-acting pill that is galantamine computer or the oral solution Are usually given twice per day, with meals. Follow the instructions of your doctor. The extended-release capsule functions best if you take it.
Don’t crush, chew, break, or open an capsule. Swallow it whole. Measure medication with all the syringe supplied, or using a distinctive dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Read instruction sheets, drug guides, and all individual info provided to you. If you’ve any questions consult your physician or pharmacist. Take galantamine. Drink 6 to 8 glasses of water every day to keep from becoming dehydrated while taking this medicine.
Inform the surgeon beforehand which you are currently using galantamine should you need surgery. You might have to quit using the medication for a limited moment. For those who have stopped taking galantamine talk to your physician before you begin taking it again. You might need to restart the drug. Store at room temperature away from moisture and heat. Don’t permit the liquid medication to freeze.
Side Effects
- Diarrhea
- Dizziness
- Vomiting
- Depression
- Loss of appetite
- Stomach upset
- Uncontrollable shaking in a part of your body
- Decreased heart rate
- Headache
- Nausea
- Tiredness
- Weight loss
Interactions
Drugs with anticholinergic properties and that cross into the mind, such as atropine, benztropine, and trihexyphenidyl produce effects that are unwanted to galantamine and should be avoided during treatment with galantamine. Blood levels may be increased by drugs like ketoconazole and paroxetine that reduce of and, therefore, the side effects of galantamine. The neuromuscular blocking effect of succinylcholine and related drugs which are used during operation may be added to by Galantamine.
Unlike donepezil, galantamine doesn’t increase blood levels of medications and raise their risk for side effects.