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Brand Names
Ami-rax, Anx, Atarax, Hydroxy Compound, Hyzine, Marax, Restall, Rezine, Vistacon, Vistacot, Vistaject-50, Vistaril, Vistazine

Hydroxyzine Information

Hydroxyzine reduces action in the central nervous system. It also functions as an antihistamine that reduces the effects of chemical histamine in the body. Histamine can produce symptoms of itching, or hives on the skin.Hydroxyzine is used as a stimulant to treat anxiety and anxiety. It is also used together with other medicines given during and following anesthesia.Hydroxyzine can also be utilized to deal with skin reactions such as hives or contact dermatitis.Hydroxyzine may also be used for purposes not listed in this medication guide.

Used for treatment: Alcohol Withdrawal Syndrome(AWS), Nausea and Vomiting, Pruritus, Psychomotor Agitation, Acute Anxiety

Hydroxyzine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The sedative properties of hydroxyzine happen in the subcortical level of the CNS. Secondary to the central anticholinergic activities, hydroxyzine might be powerful as an antiemetic.

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How to use hydroxyzine

Follow all instructions on your prescription label. Your doctor may occasionally change your dosage. Don’t use this medicine in smaller or larger quantities or for longer than suggested. Shake the oral suspension Just before you step a dose. Measure liquid medicine with the syringe provided, or with a distinctive dose-measuring spoon or medicine cup.

Hydroxyzine is really for use only. You shouldn’t take this medication. Call your physician if they get worse, or if your stress symptoms do not improve.

Side Effects

  • dry mouth
  • dizziness
  • drowsiness
  • nausea


Hydroxyzine increases the sedating effects of alcohol and other medications that could cause sedation such as the benzodiazepine class of drugs. These drugs include lorazepam, diazepam, clonazepam, and alprazolam. Hydroxyzine and the sedating effects also add together the narcotic class of pain medications and its derivatives, such as oxycodone and acetaminophen, hydrocodone/acetaminophen, hydromorphone, codeine,and propoxyphene. Hydroxyzine also increases the effects of the tricyclic class of antidepressants, for example amitriptyline, imipramine, and desipramine).

Hydroxyzine increases the effects of certain antihypertensive drugs, by way of propranolol, clonidine, and example . The effects of other medications can intensify with anticholinergic properties, for example dicyclomine, bethanechol, Probanthine, amitriptyline, and chlorpromazine. Loss may be required by the dose of hydroxyzine when using these medications.