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Indinavir sulfate Information
Indinavir is a protease Inhibitor from multiplying in your body antifungal medication that prevents human immunodeficiency virus cells. Indinavir is used to deal with . Indinavir is not a treatment for AIDS or HIV.Indinavir might also be utilized for purposes.
Indinavir inhibits the HIV viral protease enzyme which prevents cleavage of their gag-pol polyprotein, resulting in noninfectious, immature viral particles.
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How to use indinavir sulfate
Follow all instructions. Don’t take this medication in bigger or smaller quantities or for longer than advised. Indinavir should be taken on an empty stomach, at least 1 hour before or two hours following a meal. Indinavir is usually taken every 8 hours. Take the medicine at the identical time each day. Require indinavir with a Complete glass You might drink juice, coffee, or tea using this medicine.
Drink at least 6 glasses of water every day to reduce kidney stones as you are taking indinavir. If you would rather choose the medicine with meals, eat corn flakes with skim milk and sugar, or a light meal, such as dry toast with jelly. Avoid eating a high fat meal. Use indinavir regularly to get the most benefit. Take your prescription refilled before you run out of medicine.
When using indinavir, you will need frequent blood tests. HIV/AIDS is usually treated with a mixture of drugs. Use instructed by your doctor. Read the medication guide or patient instructions provided with every medication. Don’t change your doses or drug schedule without your doctor’s advice. Every person with AIDS or HIV should stay under a doctor’s care. Store at room temperature away from moisture and heat.
Keep the capsules in their original container, together with canister or the package of preservative that is moisture-absorbing.
Interactions
Indinavir interacts with many medications. Some of the critical interactions are mentioned below. Patients should consult their healthcare professional before combining any drugs. Triazolam, alprazolam, midazolam, pimozide, lovastatin, simvastatin, ergot derivatives, and amiodarone shouldn’t be mixed due to the chance of adverse effects.
Indinavir increases blood levels of stavudine, alfuzosin, oral contraceptives, and clarithromycin. Increased blood levels might cause side effects that are more common. Didanosine’s blood flow decreases and may thereby reduce the effectiveness of didanosine. Therefore, when indinavir and didanosine are both being used for treatment, their ingestion ought to be separated by one hour.
Indinavir may inhibit these cholesterol-lowering drugs lovastatin, simvastatin, and atorvastatin’s break-down. This may raise the risk of muscle breakdown which could possibly be viewed when these drugs accumulate in the body. Ketoconazole, itraconazole, delavirdine and clarithromycin can increase blood levels of indinavir and result in severe or more frequent side effects from indinavir.
Rifampin, rifabutin, St. John’s Wort and efavirenz reduce the blood levels of indinavir and thus can reduce the effect of indinavir. Indinavir raises the probability of side effects such as fainting, prolonged erection, and low blood pressure and blood levels of sildenafil.