Metronidazole Hydrochloride

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Brand Names
Flagyl, Metro I.V., MetroCream, MetroGel, MetroLotion, Metryl, Noritate, Nydamax, Obagi, Protostat, Pylera, Rosadan, Rozex, Sentry AQ Mardel Clout, Vandazole, Vitazol

Metronidazole hydrochloride Information

Metronidazole is an antibiotic. It fights bacteria in the body.Metronidazole can be used to treat fungal infections of the anus, skin, stomach, joints, tendons and respiratory tract. This medication won’t treat a vaginal yeast infection.Metronidazole may also be used for purposes.

Used for treatment: Abscess, Intra-Abdominal, Amebiasis, Bacterial Septicemia, Bacterial Vaginosis, Empyema, Endocarditis, Bacterial, Endometritis, Endomyometritis, Giardiasis, Helicobacter Pylori Infections, Infection parasitic, Infections, Bacterial, Lower respiratory tract infection bacterial, Lung Abscess, Meningitis, Periodontitis, Peritonitis bacterial, Pneumonia, Postoperative Infections, Pouchitis, Rosaceas, Septicemia bacterial anaerobic, Skin and Subcutaneous Tissue Bacterial Infections, Tetanus, Tubo-ovarian abscess, Urethritis, Asymptomatic Trichomoniasis, Hepatic abscess, Refractory Sinusitis, Symptomatic Trichomoniasis

Metronidazole is a prodrug. Unionized metronidazole is selective for anaerobic bacteria because of their ability to intracellularly decrease metronidazole to its active form. This reduced metronidazole subsequently covalently binds to DNA, disrupt its helical structure, inhibiting bacterial nucleic acid synthesis and leading to bacterial cell death.

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How to use metronidazole hydrochloride

Just as prescribed by your physician. Don’t take in smaller or larger amounts or for longer than advised. Follow the instructions. Take the extended-release metronidazole pill After having a meal on a empty stomach, at least 1 hour before or 2 hours. Don’t crush, chew, or break an extended-release tabletcomputer. Swallow it whole. Breaking the pill can cause too much of this medication to be released at any time. Simply take this medication for the prescribed amount of time.

Doses may raise your chance of infection that is resistant to antibiotics. Metronidazole will not treat a viral infection such as flu or the frequent cold. To be sure effects are not being caused by this medication, your blood may need to get tested regularly. Your liver functioning may need to be tested. See your physician regularly.

This medicine can cause odd results with specific evaluations. Store at room temperature away from moisture and heat.

Side Effects

  • Loss of appetite
  • Dry mouth
  • Dark or reddish-brown urine
  • Diarrhea
  • Sharp, unpleasant metallic taste
  • Vomiting
  • Sharp, unpleasant metallic taste
  • Upset stomach
  • Numbness or tingling of hands or feet
  • Vomiting
  • Diarrhea
  • Mouth or tongue irritation
  • Skin irritation, including redness, dryness, burning, or stinging, at the site of application
  • Dark or reddish-brown urine
  • Upset stomach
  • Mouth or tongue irritation
  • Dry mouth
  • Numbness or tingling of hands or feet
  • Loss of appetite

Interactions

Alcohol ought to be avoided because metronidazole and alcohol can lead to vomiting, nausea, cramps, flushing, and headache. Metronidazole can increase the blood thinning effects of warfarin and increase the risk of bleeding probably by reducing the breakdown of warfarin. Blood levels of metronidazole increase by decreasing its absorption, while cholestyramine reduces blood levels of metronidazole.

For treating human disorder since amprenavir contains propylene glycol, Metronidazole shouldn’t be combined with amprenavir. Metronidazole blocks the breakdown of propylene glycol from the liver resulting in accumulation of propylene glycol in blood. Accumulation of propylene glycol can cause seizures and lead to kidney failure. Metronidazole raises the blood levels of cyclosporine, lithium ion and carbamazepine though unknown mechanisms.

Reactions may occur if these drugs are taken with metronidazole.

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