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Metronidazole Information
Metronidazole is an antibiotic. It fights bacteria in your body.Metronidazole is used to treat bacterial infections of respiratory tract, stomach, skin, joints, and the vagina. This medicine won’t deal with a vaginal yeast infection.Metronidazole may also be used for purposes.
Metronidazole is a prodrug. Unionized metronidazole is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form. This decreased metronidazole then covalently binds to DNA, interrupt its helical structure, inhibiting bacterial nucleic acid synthesis and leading to bacterial cell death.
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How to use metronidazole
Just as prescribed by your doctor. Don’t take in smaller or bigger amounts or for longer than recommended. Follow the instructions. Have the extended-release metronidazole pill After eating a meal at least 1 hour before or 2 hours. Do not crush, chew, or split an extended-release tablet. Breaking the pill may cause too much of this medication. Take this medication. Your symptoms may improve before the infection is completely cleared.
Doses can raise. Metronidazole won’t take care of a viral infection such as flu or the common cold. Your blood might need to get tested frequently, to be sure this medication isn’t causing harmful effects. Your liver function may need to get tested. Visit your physician regularly. This medication can cause results with specific evaluations. Tell any doctor who treats you that you’re currently using metronidazole.
Store at room temperature away from heat and moisture.
Side Effects
- Loss of appetite
- Dry mouth
- Dark or reddish-brown urine
- Diarrhea
- Sharp, unpleasant metallic taste
- Vomiting
- Sharp, unpleasant metallic taste
- Upset stomach
- Numbness or tingling of hands or feet
- Vomiting
- Diarrhea
- Mouth or tongue irritation
- Skin irritation, including redness, dryness, burning, or stinging, at the site of application
- Dark or reddish-brown urine
- Upset stomach
- Mouth or tongue irritation
- Dry mouth
- Numbness or tingling of hands or feet
- Loss of appetite
Interactions
Alcohol ought to be avoided because alcohol and metronidazole together can lead to vomiting, nausea, cramps, flushing, and headache. Metronidazole can raise the blood thinning effects of warfarin and increase the risk of bleeding by reducing the breakdown of warfarin. Blood levels of metronidazole increase by decreasing its absorption, whereas cholestyramine reduces blood levels of metronidazole. Metronidazole should not be combined with amprenavir because amprenavir includes propylene glycol for curing human disease.
Metronidazole blocks the breakdown of propylene glycol from the liver. Accumulation of propylene glycol result in kidney failure, and can cause higher heart rate, seizures. Metronidazole raises the blood levels of lithium carbamazepine and cyclosporine though unknown mechanics. Reactions may occur if these drugs are taken with metronidazole.