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Naproxen sodium Information
Naproxen is a nonsteroidal anti-inflammatory drug . Naproxen works by reducing hormones that cause inflammation and pain within the body.Naproxen is used to treat pain or inflammation caused by conditions like arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.Even the delayed-release or extended-release pills are types of naproxen that are used for curing chronic conditions like arthritis or ankylosing spondylitis. These types of naproxen won’t work quickly enough to deal with pain that is acute.Naproxen may also be used for purposes.
The mechanism of action of naproxen, such as that of other NSAIDs, is believed to be linked to the inhibition of cyclooxygenase activity. Two unique cyclooxygenases have been described in mammals. The constitutive cyclooxygenase, COX-1, synthesizes prostaglandins necessary for normal gastrointestinal and renal function. The inducible cyclooxygenase, COX-2, generates prostaglandins involved in inflammation. Inhibition of COX-1 is thought to be associated with gastrointestinal and renal toxicity while inhibition of COX-2 provides anti inflammatory action.
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How to use naproxen sodium
Use as prescribed by your doctor, or exactly as directed on the label. Do not take this medication in larger amounts or for longer than advised. Use. Don’t crush, chew, or split a naproxen tabletcomputer. Swallow it whole. Shake the suspension until a dose is measured by you. Measure liquid medicine with the syringe provided, or with a unique dose-measuring spoon or medicine cup.
If you do not own a dose-measuring device, ask your pharmacist for one. Your dosage needs can change, if you switch manufacturers, strengths, or forms of naproxen. If you have any questions regarding the sort of naproxen you’re currently using, ask your pharmacist. If a child is using this medicine, tell your doctor if the child has any changes in weight.
Naproxen doses are derived from burden in children, and your child’s dosage might affect. If you use naproxen long term, you may require medical evaluations. This medicine can cause results with certain evaluations. Store at room temperature away from heat, moisture, and light. Keep the bottle tightly closed when not in use. Read all info, drug guides, and instruction sheets provided to you. If you have some questions ask your doctor or pharmacist.
Side Effects
- heartburn
- nausea
- headache
- swelling of arms or legs
- stomach pain
- constipation
- rash
- dizziness
Interactions
Naproxen is connected with several probable or suspected interactions which influence the actions of other drugs. The following examples are the most common suspected interactions. The blood levels of lithium may increase by reducing the excretion of lithium from the kidneys. Increased levels of lithium may lead to lithium toxicity.
Naproxen may reduce the blood pressure lowering effects of blood pressure medications. Because prostaglandins play a part in the regulation of blood pressure this may happen. When naproxen is used in conjunction with methotrexate (Rheumatrex, Trexall) or aminoglycosides the blood levels of the methotrexate or aminoglycoside may grow, presumably since the elimination in the body of these drugs is reduced. This may cause aminoglycoside-related or more methotrexate side effects.
People taking anticoagulants, warfarin, by way of instance,, should avoid naproxen since naproxen disrupts the blood, and excessive blood thinning can lead to bleeding. Naproxen increases the adverse impact of cyclosporine on kidney function and lessens the impact of furosemide (Lasix) and thiazide diuretics due to prostaglandin inhibition. Naproxen ought to be avoided by patients with a history of asthma attacks, hives or other allergic reactions to aspirin or other NSAIDs.
There may be an increased risk for developing an ulcer if aspirin is taken with naproxen. May be at greater risk of developing stomach ulcers when taking other or naproxen NSAIDs.