Nitrofurantoin Sodium

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Brand Names
Furadantin, Macrobid, Macrodantin, Nitro Macro

Nitrofurantoin sodium Information

Nitrofurantoin is an antibiotic that fights bacteria in your system.Nitrofurantoin is used in the treatment of urinary tract infections.Nitrofurantoin might also be utilized for purposes.

Used for treatment: Acute Cystitis, Urinary Tract Infections

Nitrofurantoin is activated by bacterial flavoproteins (nitrofuran reductase) to active reduced reactive intermediates which are thought to modulate and harm ribosomal proteins or other macromolecules, especially DNA, causing inhibition of DNA, RNA, protein, and cell wall synthesis. The general effect is inhibition of bacterial growth or cell death.

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How to use nitrofurantoin sodium

Follow all directions. Don’t take this medicine in smaller or larger amounts or for longer than advised. Shake the oral suspension well just until you step a dose. Measure liquid medication with all the syringe provided, or using a special dose-measuring spoon or medicine cup. If you don’t own a dose-measuring device, ask your pharmacist for one. You may mix or lemon juice and your dose that is liquid together to make it more easy to swallow. Drink the entire mixture straight away.

Use this medication for the full period of time. Your symptoms may improve before the infection is totally cleared. Skipping doses may raise. Nitrofurantoin will not deal with a viral infection such as influenza or the common cold. Following laboratory tests reveal that the disease has cleared nitrofurantoin is given for as many as 3 days. If you use this medicine long-term, regular medical evaluations may be needed by you at your physician’s office.

Nitrofurantoin may cause unusual results . Tell any doctor who treats you that you’re utilizing nitrofurantoin. Store at room temperature away from moisture, heat, and light.

Side Effects

  • vomiting
  • diarrhea
  • drowsiness
  • constipation
  • upset stomach
  • dizziness


High levels of probenecid or sulfinpyrazone can obstruct the kidneys’ removal of nitrofurantoin. This may increase the risk of toxicity and the blood levels of nitrofurantoin out of nitrofurantoin. Administration of a magnesium trisilicate antacid may reduce the absorption of nitrofurantoin. Nitrofurantoin live typhoid vaccine and may reduce the action of tuberculosis vaccine. Norfloxacin, for instance, nitrofurantoin decreased the impact of antibiotics, in laboratory tests.

Nitrofurantoin shouldn’t be combined with antibiotics.