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Brand Names
Furadantin, Macrobid, Macrodantin, Nitro Macro

Nitrofurantoin Information

Nitrofurantoin is.Nitrofurantoin is used in the treatment of urinary tract ailments.Nitrofurantoin may also be used for purposes not listed in this medication guide.

Used for treatment: Acute Cystitis, Urinary Tract Infections

Nitrofurantoin is triggered by bacterial flavoproteins (nitrofuran reductase) to busy reduced reactive intermediates that are thought to modulate and damage ribosomal proteins or other macromolecules, particularly DNA, inducing inhibition of DNA, RNA, protein, and cell wall synthesis. The general effect is inhibition of bacterial growth or cell death.

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How to use nitrofurantoin

Follow all instructions. Don’t take this medication in larger or smaller amounts or for longer than suggested. Take nitrofurantoin with food. Shake the suspension well just until you measure a dose. Measure liquid medicine with all the syringe provided, or using a distinctive dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist.

You may combine or lemon juice and your dose that is liquid to make it much easier to swallow. Drink the entire mixture straight away. Use this medication for the prescribed amount of time. Skipping doses may raise your chance of disease that’s resistant to antibiotics. Nitrofurantoin won’t deal with a viral infection like flu or the frequent cold.

After laboratory tests show that the disease has cleared, nitrofurantoin is given for up to 3 times. If you use this medication long term, you might need regular medical tests. Unusual results can be caused by nitrofurantoin . Tell any doctor who treats you that you are using nitrofurantoin. Store at room temperature away from light, heat, and moisture.

Side Effects

  • vomiting
  • diarrhea
  • drowsiness
  • constipation
  • upset stomach
  • dizziness


High doses of probenecid or sulfinpyrazone can block the kidneys’ removal of nitrofurantoin. This may increase the blood levels of nitrofurantoin and the danger of toxicity . Administration of a magnesium trisilicate antacid may reduce the absorption of nitrofurantoin. Nitrofurantoin live typhoid vaccine and may lessen the activity of tuberculosis vaccine that is live. Nitrofurantoin decreased the impact of quinolone antibiotics, norfloxacin, as an example.

Nitrofurantoin shouldn’t be combined with antibiotics.