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Nortriptyline hydrochloride Information
Nortriptyline is a tricyclic antidepressant. Nortriptyline affects chemicals in the brain which could be unbalanced in individuals with depression.Nortriptyline is used as a treatment for symptoms of depression.Nortriptyline may also be used for purposes not listed in this medication guide.
It’s thought that nortriptyline either inhibits the reuptake of the neurotransmitter serotonin at the neuronal membrane or behaves at beta-adrenergic receptors. Tricyclic antidepressants don’t inhibit monoamine oxidase nor do they influence dopamine reuptake.
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How to use nortriptyline hydrochloride
Follow all directions on your prescription label. Your physician may change your dose. Do not take this medication in smaller or bigger amounts or for longer than suggested. Tell the surgeon ahead of time which you are using nortriptyline should you need surgery. You may have to stop using the medicine for a short time. Do not quit using nortriptyline abruptly, or you could have withdrawal symptoms.
Ask your doctor how to safely stop using nortriptyline. It can take a few weeks before your symptoms change. Continue using the medication and tell your health care provider if your symptoms don’t improve. Store at room temperature away from heat and moisture.
- difficulty urinating
- weight gain
- dry mouth
- changes in sex drive
- blurred vision
- changes in heart rhythm
- increased sweating
TCAs, such as nortriptyline, shouldn’t be used with a monoamine oxidase inhibitors like tranylcypromine, isocarboxazid, phenelzine, and procarbazine because of the chance of hyperpyretic crises, convulsions, and even death. Cimetidine can boost blood levels of nortriptyline in the blood by interfering with the metabolism of nortriptyline from the liver. Increased amounts of nortriptyline may cause unwanted effects. Include propafenone, flecainide, quinidine, and fluoxetine.
Nortriptyline exaggerates the effects of drugs and other medications that slow the brain’s action, such as narcotics, as well as alcohol, barbiturates, benzodiazepines, such as lorazepam, clonazepam, and diazepam. When given to individuals taking 11, arouses the mind. Mixing nortriptyline or other TCAs with medications that block acetylcholine can cause constipation and even paralyze the intestine.
Dangerous elevations in blood pressure may happen if TCA’s are combined with clonidine.