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Brand Names
Omesec, Prilosec, UlcerGard, Zegerid, Zegerid with Magnesium Hydroxide

Omeprazole Information

Omeprazole is.Omeprazole is used to treat symptoms of gastroesophageal reflux disease And other conditions caused by stomach acid. Omeprazole is also used to encourage healing of erosive esophagitis . Omeprazole may also be given along with antibiotics to treat esophageal ulcer .Omeprazole is not for immediate relief of heartburn symptoms.Omeprazole may also be used for purposes not listed in this medication guide.

Used for treatment: Duodenal Ulcer, Erosive Esophagitis(EE), Gastric Ulcer, GastroEsophageal Reflux Disease, Heartburn, Helicobacter Pylori Infections, Systemic Mastocytosis, Zollinger-Ellison Syndrome, Multiple endocrine adenomas

Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H /K -ATPase in the gastric parietal cell. By acting specifically on the proton pump, omeprazole blocks the final step in acid production, thus reducing gastric acidity.

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How to use omeprazole

Omeprazole is usually taken before eating . Follow all instructions. Do not take this medication in bigger or smaller amounts or for longer than advised. Prilosec OTC must be obtained every 24 hours for 14 days. Before you eat breakfast, just take the medicine at the morning. Do not take more than one tablet every 24 hours. Allow at least 4 months to pass before you begin another 14-day therapy with Prilosec OTC.

Call your physician if you have additional symptoms and require therapy before the 4 weeks has passed. Don’t crush, chew, or break a Prilosec OTC tablet, or an coated pill. Swallow the pill complete. The capsule may open and sprinkle the medicine to make swallowing easier. Swallow the mixture right away without chewing. Don’t save for later usage. Dissolve the powder in a small amount of plain water. Use 1 tsp of plain water for the 2.5-mg packet, or one Tablespoon of water for the 10-mg packet.

Allow the mixture stand for 2 or 3 minutes, then stir fry and drink straight away. To make certain you get the entire dose, then add a little more water to the same glass, swirl lightly and drink straight away. This mix may also be given via a nasogastric feeding tube using just a syringe. Shake the syringe nicely connect to the NG tube and push on the plunger down to empty the syringe. Refill the syringe with water and flush the tube to wash down the contents.

Use this medicine. Your symptoms may improve before your condition is completely cleared. You could develop a vitamin B-12 deficiency if you utilize omeprazole for more than 3 decades. Talk to your doctor if you create it about how to manage this condition. Call your health care provider if your symptoms do not improve, or if they get worse while using omeprazole.

Some conditions are treated with a mixture of antibiotics and omeprazole. Use all drugs as directed by your doctor. Read the medication guide or individual instructions provided with every medication. Do not change your doses or drug schedule without the advice of your doctor. This medication can cause unusual results and you may need to quit using the medication for a brief period in front of a test.

Tell any doctor who treats you that you’re using omeprazole. Store at room temperature away from heat and moisture.

Side Effects

  • gas
  • diarrhea
  • respiratory system events
  • headache
  • nausea
  • vomiting
  • abdominal pain
  • fever


Omeprazole potentially can increase the levels in blood by decreasing the removal of these drugs of diazepam, warfarin, and phenytoin. The absorption of certain drugs may be affected by stomach acidity. Consequently, omeprazole in addition to some other PPIs decrease the absorption and concentration and increase the absorption and concentration. This may lower the efficacy of ketoconazole or increase digoxin toxicity. Through unknown mechanisms, blood levels of saquinavir may increase and reduce drugs that are used for treating patients with infection, blood levels of atazanavir and nelfinavir.

Thus, the dose of saquinavir might need to be reduced to avoid toxicity, and the doses of nelfinavir and atazanavir may need to be increased to maintain. Clopidogrel is converted into its active form by enzymes in the liver. Omeprazole reduces the action of these enzymes and can decrease the action of clopidogrel. Omeprazole should not be used with clopidogrel. The concentration of cilostazol raises. The dose of cilostazol ought to be reduced by 100 mg twice per day to 50 mg twice when given with omeprazole.

Blood levels of tacrolimus and methotrexate may increase.