Ondansetron Hydrochloride

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Brand Names
Zofran, Zofran ODT, Zuplenz

Ondansetron hydrochloride Information

Ondansetron blocks the action of chemicals in the body that may trigger nausea and vomiting.Ondansetron is used to reduce nausea and vomiting which could be brought on by surgery, cancer, chemotherapy, or radiation treatment.Ondansetron could be utilized for functions.

Used for treatment: Chemotherapy Induced Nausea and Vomiting, Cholestatic pruritus, Post-Operative Nausea and Vomiting, Uremic Pruritus, Radiation induced nausea and vomiting, Severe Hyperemesis gravidarum

Ondansetron is a selective serotonin 5-HT3 receptor antagonist. The antiemetic action of the medication is brought about through the inhibition of 5-HT3 receptors found both centrally (medullary chemoreceptor zone) and peripherally (GI tract). This inhibition of 5-HT3 receptors subsequently inhibits the adrenal afferent stimulation of the vomiting center, probably indirectly at the level of the area postrema, in addition to through direct inhibition of serotonin activity within the region postrema and the chemoreceptor trigger zone.

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How to use ondansetron hydrochloride

Follow all instructions. Do not take this medicine in smaller or larger amounts or for longer than advised. Ondansetron may be taken with or without food. The first dose of ondansetron is removed prior to the start of radiation therapy, chemotherapy, or your operation. Follow your doctor’s dosing instructions . Pick out the ondansetron regular tablet with a full glass of plain water. To take the orally disintegrating tablet :

  • Maintain the pill in its blister pack until you’re ready to accept it.

    Open the bundle and peel back the foil. Do not push on a pill or you could damage the pill.

  • Utilize dry hands to remove the tablet and put it on your mouth.
  • Don’t swallow the pill whole. Let it dissolve in your mouth.
  • Swallow a few times as the pill dissolves.

To utilize ondansetron oral iodine picture :

  • Maintain the strip from the foil pouch until you’re ready to use this medicine.

    It will start to dissolve away.

  • Don’t swallow the strip intact. Allow it to dissolve in your mouth.
  • Swallow a few days following the strip succeeds. You might drink liquid to assist swallow the strip that is dissolved, if desired.

Quantify liquid medicine with an dosing syringe supplied, or using a special dose-measuring spoon or medicine cup.

If you don’t own a dose-measuring device, ask your pharmacist for one. Store at room temperature away from heat, moisture, and light. Store medicine at an upright position.

Side Effects

  • constipation
  • diarrhea
  • dizziness
  • headache
  • tiredness