Paroxetine Hydrochloride

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Brand Names
Brisdelle, Paxil, Paxil CR, Pexeva

Paroxetine hydrochloride Information

Paroxetine is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors . Paroxetine affects chemicals in the brain which may be unbalanced in people with anxiety depression, or other ailments.Paroxetine is used to treat depression, obsessive-compulsive disease, stress disorders, post-traumatic anxiety disorder , and premenstrual dysphoric disorder .Paroxetine’s Brisdelle brand is used to treat.

For treating any problems, Brisdelle is not.Paroxetine may also be used for purposes.

Used for treatment: Generalized Anxiety Disorder, Vasomotor Symptoms

Paroxetine is a potent and highly selective inhibitor of neuronal serotonin reuptake. Paroxetine probably inhibits the reuptake of serotonin at the neuronal membrane, enhances serotonergic neurotransmission by lowering turnover of the neurotransmitter, therefore it hastens its activity at synaptic receptor sites and potentiates 5-HT in the CNS; paroxetine is significantly more potent than both sertraline and fluoxetine in its ability to inhibit 5-HT reuptake. Compared to the tricyclic antidepressants, SSRIs have radically diminished binding to histamine, acetylcholine, and norepinephrine receptors. The mechanism of action for treating vasomotor symptoms is unknown.

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How to use paroxetine hydrochloride

Follow all instructions. Your dosage may sometimes change. Don’t take this medication in larger or smaller quantities or for longer than advised. Do not crush, chew, or break an extended-release tablet. Shake the oral suspension Well just until you step a dose. Measure medication with the syringe supplied, or using a unique dose-measuring spoon or medicine cup.

If you do not own a dose-measuring device, ask your pharmacist. It might take around 4 weeks before your symptoms change. Continue using the medication as directed and tell your health care provider if your symptoms do not improve. Do not quit using paroxetine unexpectedly, or you may have withdrawal symptoms. Consult your doctor how to safely quit using paroxetine. Follow your doctor’s instructions.

Side Effects

  • shaking
  • not feeling hungry
  • yawning
  • feeling anxious or trouble sleeping
  • headache
  • weakness
  • dry mouth
  • constipation
  • sweating
  • dizziness
  • infection
  • nausea
  • sexual problems
  • sleepiness


All SSRIs, including paroxetine, shouldn’t be taken as an example, isocarboxazid, phenelzine, tranylcypromine, selegiline, and procarbazine or medications that inhibit monoamine oxidase such as methylene blue and linezolid. Such combinations may lead to confusion, higher blood pressure, tremor, hyperactivity, coma, and death. Similar reactions happen when paroxetine is blended with other medications for example, tryptophan, St.

John’s wort, meperidine , tramadol that increase dopamine within the brain. Paroxetine can increase this blood thinner, warfarin’s impact, leading to excessive bleeding. Therefore, warfarin therapy ought to be monitored more frequently in patients who are also currently taking paroxetine. Combining SSRIs such as paroxetine with nonsteroidal anti inflammatory drugs aspirin or other drugs that affect bleeding may increase the probability of upper gastrointestinal bleeding.

Phenobarbital and Phenytoin may decrease the amount of paroxetine in the human body and lower its effectiveness.