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Brand Names
Pentopak, Pentoxil, Trental

Pentoxifylline Information

Pentoxifylline causes. This helps your blood vessels carry oxygen.Pentoxifylline is used to improve blood flow and reduce indicators of a condition . Pentoxifylline is not a cure for this condition.Pentoxifylline might be used for purposes not listed in this medication guide.

Used for treatment: Alcoholic Liver Diseases, Intermittent Claudication, Venous Leg Ulcer

Pentoxifylline inhibits erythrocyte phosphodiesterase, resulting in a rise in erythrocyte cAMP action. Subsequently, the erythrocyte membrane becomes more resistant to deformity. Along with erythrocyte action, pentoxifylline also decreases blood viscosity by reducing plasma fibrinogen levels and raising fibrinolytic activity. It is also a non selective adenosine receptor antagonist.

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How to use pentoxifylline

Follow all instructions. Don’t take this medication in smaller or bigger quantities or for longer than suggested. Pentoxifylline is usually taken 3 times every day. Follow the directions of your doctor. Blood tests may be needed by you, while using pentoxifylline. Don’t crush, chew, or split an extended-release tabletcomputer. It may take around 4 weeks before your symptoms change. Keep using the medication and inform your physician if your symptoms do not improve after 8 weeks of therapy.

Store at room temperature away from lighting, heat, and moisture.

Side Effects

  • upset stomach
  • gas
  • vomiting
  • dizziness
  • chest pain
  • headache
  • fast heartbeat


Pentoxifylline reduces the breakdown of theophylline in the liver blood levels and unwanted side effects of theophylline. The risk of bleeding may increase. The mechanism for this interaction is unknown.