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Di-Phen, Dilantin, Euthasol, Phenytek
Phenytoin sodium Information
Phenytoin is an anti-epileptic medication. It works by slowing down impulses in the brain that cause seizures.Phenytoin is used to control seizures. Phenytoin does not take care of all sorts of seizures, if it is the ideal medicine for you and your health care provider will determine.Phenytoin may also be utilized for purposes.
Phenytoin acts on sodium channels on the neuronal cell membrane, restricting the spread of seizure activity and decreasing seizure propagation. By promoting sodium efflux from neurons, phenytoin tends to stabilize the threshold against hyperexcitability caused by excessive stimulation or environmental changes capable of reducing membrane sodium gradient. Including the reduction of post-tetanic potentiation at synapses. Decline of post-tetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas.
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How to use phenytoin sodium
Follow all directions. Do not take this medication in smaller or larger amounts or for longer than advised. Don’t use. Telephone your doctor for a prescriptionmedication. The chewable tablet should be chewed before you swallow it. Shake the suspension until you measure a dose. Measure medication with the syringe provided, or with a distinctive dose-measuring spoon or medicine cup. If you don’t have a dose-measuring device, ask your pharmacist.
While using phenytoin, you might need regular blood tests. You may also require a blood test when switching from one type of phenytoin. Go to your doctor regularly. If you are taking phenytoin to treat seizures, do not quit using phenytoin suddenly, even in case you feel good. Stopping abruptly may cause migraines. Follow your doctor’s instructions about tapering your own dose.
If this medicine doesn’t seem to function as well in treating your situation, tell your doctor. Wear a medical alert tag or carry an ID card stating that you just take phenytoin. Need to be aware that you take seizure medication. Phenytoin can lead to swelling in your gums. Brush and floss your teeth and visit with with your dentist regularly to help stop this issue. Store at room temperature away from heat, light, and moisture.
- problems with walking and coordination
- Softening of your bones (osteomalacia). This can cause broken bones.
- trouble sleeping
- slurred speech
There are potential drug interactions with phenytoin. Phenytoin can raise the metabolism of many medications, reducing their levels within the body. Medicines that might be affected include: digoxin, carbamazepine, clonazepam, corticosteroids, cyclosporine, disopyramide, doxycycline, estrogens, oral contraceptives, paroxetine , quinidine, tacrolimus, theophylline, phenobarbital, valproic acid , and warfarin. These medications can be interacted with by Phenytoin not just when it is added to treatment but also when it is discontinued.
In the latter scenario, the concentration of the other drugs may increase. The effect may be unpredictable. Other medications may affect the metabolism of Phenytoin. Drugs that increase phenytoin blood levels and toxicity include: acute alcohol intake, amiodarone , chlordiazepoxide, cimetidine , diazepam , dicumarol, disulfiram, estrogens, ethosuximide, fluoxetine, fluorouracil, fluvoxamine, isoniazid, methylphenidate, omeprazole, sertraline , tolbutamide, and trazodone .
Drugs which reduce effectiveness and may decrease phenytoin levels include carbamazepine, chronic alcohol abuse, reserpine, and sucralfate. Some of these can reduce the oral ingestion of phenytoin: antacids containing calcium carbonate, magnesium, or aluminum; calcium salts; or feeding products. Separating the administration of enteral and phenytoin feeding products, antacids, or calcium salts can help avoid this interaction.