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Brand Names
Compazine, Compro, Procot

Prochlorperazine Information

Prochlorperazine is an medicine in a category of drugs known as phenothiazines . It operates by changing the actions of chemicals in mind.Prochlorperazine oral Is used to treat psychotic disorders such as schizophrenia. Additionally it is utilized to treat anxiety, and also to control severe nausea and vomiting. Prochlorperazine might also be used for purposes not listed in this medication guide.

Used for treatment: Schizophrenia, Non-psychotic generalized anxiety, Severe Nausea and vomiting

The mechanism of action of prochlorperazine has not been fully determined, but may be primarily linked to its antidopaminergic effects. Prochlorperazine blocks the D2 somatodendritic autoreceptor, resulting in the blockade of postsynaptic dopamine receptors in the mesolimbic system along with an increased dopamine turnover. Prochlorperazine additionally has anti-emetic effects, which may be attributed to dopamine blockade in the chemoreceptor trigger zone. Prochlorperazine also blocks anticholinergic and alpha-adrenergic receptors, the blockade of alpha(1)-adrenergic receptors leading to sedation, muscle relaxation, and hypotension.

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How to use prochlorperazine

Follow all directions on your prescription label. Your dose may sometimes change. Don’t use this medicine in smaller or larger amounts or for longer than advised. You might require frequent evaluations if you choose prochlorperazine long-term. Store at room temperature away from light, heat, and moisture.