Rabeprazole Sodium

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Brand Names
Aciphex, Aciphex Sprinkle

Rabeprazole sodium Information

Rabeprazole is a proton pump inhibitor that decreases the amount of acid produced in your stomach.Rabeprazole is used short-term to deal with symptoms of gastroesophageal reflux disease In kids and adults who are at least 1 year old. Rabeprazole is used only in adults to treat conditions involving excessive stomach acid.

Rabeprazole is also utilized to promote healing of erosive esophagitis or ulcers .Rabeprazole may also be granted to prevent ulcer .Rabeprazole isn’t appropriate for prompt relief of asthma symptoms.Rabeprazole may also be used for purposes not listed in this medication guide.

Used for treatment: Duodenal Ulcer, Gastric Ulcer, Zollinger-Ellison Syndrome

Rabeprazole belongs to a class of antisecretory compounds (substituted benzimidazole proton-pump inhibitors) which don’t exhibit anticholinergic or histamine H2-receptor antagonist properties, but suppress gastric acid secretion by inhibiting the gastric H /K ATPase (hydrogen-potassium adenosine triphosphatase) in the secretory surface of the gastric parietal cell. Since this enzyme is thought of as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton-pump inhibitor. Rabeprazole blocks the last step of gastric acid secretion. In gastric parietal cells, rabeprazole is protonated, accumulates, and is transformed to an active sulfenamide. When studied in vitro, rabeprazole is chemically activated at pH 1.2 with a half-life of 78 seconds.

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How to use rabeprazole sodium

Rabeprazole is normally taken once every day. Follow all instructions. Don’t take this medicine in larger or smaller amounts or for longer than suggested. Do not give this medicine to your child. Advantages and forms of rabeprazole shouldn’t be granted to a child younger than 12 years old. AcipHex Sprinkle shouldn’t be given to a child younger. Rabeprazole is for use only, usually 4 to 8 weeks. In case you require healing time your physician may recommend a second course of treatment.

When treating H. pylori disease, rabeprazole might be required for just seven days. Follow your doctor’s dosing directions very carefully. Take this medication. Take the medication after a meal should you choose rabeprazole to deal with ulcers. Take the medicine, if you take rabeprazole to stop blisters caused by Helicobacter pylori. You may choose the medicine with or without food, if you choose rabeprazole for every other ailment. The rabeprazole capsule Should be taken 30 minutes before a meal.

Do not crush, break, or take a rabeprazole tabletcomputer. Swallow it whole. To take rabeprazole , open the capsule and sprinkle the medicine to a spoonful of soft food such as applesauce, yogurt, or baby food made from vegetable or fruit. You could also mix or baby formula and the medication. Swallow right away without chewing. Don’t store the mixture for later use; it will go bad after 15 seconds. Some conditions are treated with a mixture of rabeprazole and antibiotics.

Utilize instructed by your doctor. Read drug guides all individual information, and documentation supplied to you. If you have any queries consult your physician or pharmacist. Don’t change your doses or drug schedule without your doctor’s advice. Take your medication for the total amount of time. Call your doctor if your symptoms do not improve, or if they get worse while utilizing rabeprazole. You could develop an vitamin B-12 deficiency, if you use rabeprazole for longer than 3 decades.

Speak to your physician if you develop it, about ways to manage this condition. Store at room temperature away from heat and moisture.

Side Effects

  • constipation
  • pain
  • infection
  • headache
  • gas
  • sore throat


There have been reports of an increase in the effect of this blood thinner, warfarin , by rabeprazole which can result in increased bleeding. Patients taking warfarin ought to be monitored more frequently if they start taking rabeprazole. Rabeprazole potentially leading to cyclosporin toxicity and may reduce cyclosporin’s removal in the liver, thus increasing cyclosporin levels.

Changes in gut acidity may affect the absorption of certain drugs. Rabeprazole along with other PPIs that reduce stomach acid increase the absorption and concentration and decrease the absorption and concentration. This may result in reduced effectiveness of increased or ketoconazole digoxin toxicity, respectively. Blood levels of atazanavir may decrease.

Aciphex aka Rabeprazole