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Brand Names

Salbutamol Information

Used for treatment: Bronchospasm, Bronchospasm, Exercise-Induced, Hyperkalemia

Salbutamol is a beta(2)-adrenergic agonist and thus it arouses beta(2)-adrenergic receptors. Binding of albuterol to beta(2)-receptors in the lungs results in relaxation of bronchial smooth muscles. It’s thought that salbutamol raises cAMP production by activating adenylate cyclase, and the actions of salbutamol are mediated by cAMP. Increased intracellular cyclic AMP increases the action of cAMP-dependent protein kinase A, which inhibits the phosphorylation of myosin and lowers intracellular calcium levels. A reduced intracellular calcium concentration contributes to a smooth muscle relaxation and bronchodilation. Along with bronchodilation, salbutamol inhibits the release of bronchoconstricting representatives from mast cells, inhibits microvascular leakage, and enhances mucociliary clearance.

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How to use salbutamol