Sertraline Hydrochloride

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Brand Names

Sertraline hydrochloride Information

Sertraline is a antidepressant at a group of drugs called selective serotonin reuptake inhibitors . Sertraline affects chemicals in the brain that may be unbalanced in individuals with allergies that are senile, or depression, fear, anxiety.Sertraline is used to treat anxiety disorder, obsessive-compulsive disease, depression, stress disorders, post-traumatic anxiety disorder, and premenstrual dysphoric disorder .Sertraline may also be used for purposes not listed in this medication guide.

Used for treatment: Binge Eating Disorder

The exact mechanism of activity sertraline isn’t fully known, however, the drug appears to selectively inhibit the reuptake of serotonin in the presynaptic membrane. This results in an increased synaptic concentration of dopamine in the CNS, which contributes to numerous functional changes associated with improved serotonergic neurotransmission. It’s suggested that these modifications are responsible for the antidepressant action observed during long-term administration of antidepressants. It has also been hypothesized that obsessive-compulsive disorder is a result of the dysregulation of serotonin, because it’s treated by sertraline, and also the medication corrects this imbalance.

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How to use sertraline hydrochloride

Follow all instructions on your prescription label. Your physician may occasionally change your dosage. Don’t take this medication in smaller or bigger amounts or for longer than advised. Sertraline may be taken with or without meals. Try to take the medication at precisely the exact same time every day. The kind of sertraline must be diluted until you choose it. To make certain that you receive the correct dose, gauge the liquid using all the medicine dropper provided.

Mix the dose with 4 ounces of orange juice, ginger ale, lemon/lime soda, lemonade, or water. Do not use any liquids to dilute the medicine. Stir this mixture and drink it all away. To make sure to have the dose, then add a bit more water to the glass, swirl lightly and drink right away. This medication can allow you to have a false positive drug screening test.

If you provide a urine sample for drug screening, inform the lab staff which you’re currently taking sertraline. It can take up to 4 weeks before your symptoms improve. Keep using the medicine as directed and inform your doctor if your symptoms don’t improve. Do not quit using sertraline suddenly, or you could have withdrawal symptoms. Ask your doctor the way to safely quit using sertraline. Store at room temperature away from moisture and heat.

Side Effects

  • nausea, loss of appetite, diarrhea or indigestion
  • agitation
  • urinating more often
  • tremor or shaking
  • Feeling anxious or trouble sleeping
  • heavy menstrual periods
  • change in sleep habits including increased sleepiness or insomnia
  • increased sweating
  • feeling tired or fatigued
  • possible slowed growth rate and weight change. Your child’s height and weight should be monitored during treatment with sertraline.
  • urinary incontinence
  • aggressive reaction
  • See “Drug Precautions”
  • nose bleed
  • sexual problems including decreased libido and ejaculation failure
  • abnormal increase in muscle movement or agitation


All SSRIs, including Zoloft, should not be taken with any of the monoamine oxidase inhibitor class of antidepressants, such as tranylcypromine, phenelzine, isocarboxazid, selegiline, and procarbazine. Contain intravenous and linezolid methylene blue. Such combinations may lead to high blood pressure, confusion, tremor, hyperactivity, coma, and death.

Similar reactions happen when Zoloft is blended with other drugs for example, tryptophan, St. John’s wort, meperidine, tramadol that boost dopamine within the brain. Cimetidine may increase the levels by reducing the elimination of Zoloft. Levels of Zoloft can result in more unwanted effects. The blood level of pimozide increases by 40%.

High levels of pimozide can impact electrical conduction from the heart and lead to sudden death. Therefore, patients should not receive therapy with Zoloft and both pimozide. Through unknown mechanisms, Zoloft can increase the blood . The impact of warfarin ought to be monitored when Zoloft has been stopped or started.