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Venlafaxine is a serotonin and norepinephrine reuptake inhibitor antidepressant. Venlafaxine affects chemicals. Venlafaxine is used to deal with anxiety disorder, stress, and major depressive disorder.Venlafaxine may also be used for purposes.
The exact mechanism of action of venlafaxine is unknown, but appears to be associated with the its potentiation of neurotransmitter activity in the CNS. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), inhibit the reuptake of both serotonin and norepinephrine with a potency better for the 5-HT than for the NE reuptake procedure. Both venlafaxine and the ODV metabolite have weak inhibitory effects on the reuptake of dopamine but, unlike the tricyclics and like SSRIs, they are not active in histaminergic, muscarinic, or alpha(1)-adrenergic receptors.
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How to use venlafaxine
Follow all directions. Don’t take this medicine in bigger or smaller quantities or for longer than advised. Venlafaxine should be taken with meals. Attempt to take venlafaxine. Do not crush, chew, break, or open capsule or an extended-release tablet. To create the extended-release capsule more easy to consume, you may open the capsule and sprinkle the medication into a small amount of applesauce. Swallow all of the mix without chewinggum, and do not spare any for later usage.
It can take several weeks until your symptoms improve. Continue using the medication as directed. Don’t quit using venlafaxine without first talking to your physician. You may have unpleasant side effects if you stop taking this medicine. Your blood pressure will have to get checked often. This medicine can enable you to have a positive drug screening test.
If you provide a urine sample for drug screening, then tell the laboratory staff that you’re taking venlafaxine.
- loss of appetite
- sexual side effects
- dry mouth
Venlafaxine shouldn’t be utilised in combination with a monoamine oxidase inhibitor like phenelzine, tranylcypromine , isocarboxazid, and selegiline, or within 14 days. At least 5 days should be allowed after stopping venlafaxine. Combinations of SNRIs and MAOIs may lead to acute, sometimes fatal, reactions including very high body temperature, muscular rigidity changes of heart rate and blood pressure and coma.
Reactions may occur if venlafaxine is combined with antipsychotics, tricyclic antidepressants. Examples include tryptophan, sumatriptan , lithiumion, linezolid, tramadol, and St. John’s Wort. Mixing venlafaxine with other medications which are associated with bleeding, nonsteroidal anti-inflammatory medications, warfarin or aspirin may increase the chance of bleeding, because venlafaxine is associated with bleeding. Most medications affecting the brain such as venlafaxine have the potential.
Therefore, care is advised especially early in the course of treatment. Security has not been established in children.